Msia/Kul 2 Post docs & 3 Research Associates in Cancer research

The Cancer Research Initiatives Foundation (CARIF) is the first independent Malaysian fundamental cancer research organization.  We seek an understanding of the genetic basis of cancers in Malaysia through molecular analysis.  The specific projects are described below:

1)  Identification & characterization of genetic changes in oral, nasopharyngeal & liver cancer using whole genome approaches such as SAGE and microarrays
2)  Characterization of sequence variations in the Asian population that are linked to an increased disposition to breast cancer
3)  Novel cancer therapies derived from local flora: Isolation and characterization of novel light-activated compounds from Malaysian plants

CARIF is now offering the abovementioned positions for scientists who are enthusiastic to join our team.

I.  Post doctoral research scientist (2 positions) You will have a PhD in genetics or related field, preferably with post-doctoral experience.  You will be part of project 1 or 2 described above and report to the CEO and the Board of Trustees.

II.  Research Associate (3 positions) You will assist the Project Leader in project 1 or project 2 above.  You will have an MSc in molecular biology, genetics or related biology field.

 

Postage Stamp to Raise Money for Cancer Research

LOS ANGELES- the Postal Service unveiled the design of the Breast Cancer Research “Semipostal” Stamp, here, at the Revlon Run and Walk for Women on May 9th. A nationwide issuance of this  self-adhesive stamp begins in early August.

As a 40 cent “semipostal,” the Breast Cancer Research stamp will be deemed valid for postage at the prevailing First Class Rate, currently 32 cents, with the extra 8 cents going to fund medical research at the National Institutes of Health (70 percent) and Department of Defense (30 percent).

The background of the vertically formatted stamp design features blue,yellow, orange, and green washes of watercolor.  Along the top are the words, “breast cancer” in capital letters.  A black ink drawing of a female figure is the main element, while the phrases “fund the fight” and “find a cure” appear in capital letters flowing left to right into a clockwise, circular pattern.

The stamp was designed by Ethel Kessler, a breast cancer survivor, of Bethesda, MD, and illustrated by Whitney Sherman of Baltimore, MD. This is the first time in history that the U.S. Postal Service has issued a “semipostal” stamp.  It took an act of Congress after “grass roots” campaigning by several groups led by Dr. Ernie Bodai of Sacramento, CA, to get this unique postage stamp issued.

Among the thousands at the unveiling ceremony, was Mercy Davidchik of Yuba City, CA, who was one of the most active volunteer workers in raising public support and promoting legislation to issue the Breast Cancer Research Stamp.   It is hoped that through purchase of these stamps, millions of dollars will be raised for breast cancer research, which  is considered the most commonly diagnosed cancer among all women in the U.S.

 

Lycopene for Prostate Cancer - Research Summary

BACKGROUND: Harvard researchers reported in a 2002 article in the Journal of the National Cancer Institute that eating tomato products on a regular basis is associated with a reduced risk of prostate cancer. The research included more than 47,000 participants. Researchers then continued to follow the men for several more years to learn more about the specific foods that seem to protect men from prostate cancer. That research was published this year — also in the Journal of the National Cancer Institute. The study reports men who ate tomato sauce at least twice a week were about 20-percent less likely to develop prostate cancer when compared to men who rarely ate it.
CURRENT RESEARCH: Moffitt Cancer Center in Tampa, Florida is conducting a study to look at the mechanism by which lycopene actually stops the promotion of prostate cancer cells. For the study, men with cancer who are having their prostate surgically removed are participating. Generally, the men wait six weeks after diagnosis before they have the surgery. During the six-week period, each participant is given one of three doses of lycopene or a placebo. Researchers will then compare the cancer cells from the pre-surgical biopsy and to those after surgery to compare the cell growth. So far, more than 50 patients have participated. The preliminary results from this study are expected by the summer of 2004.
Advertisement
SUPPLEMENTS VS FOOD? Lycopene supplements are available on the market, but researchers say the supplements may not offer the same level of health protection. Experts point out that so far most studies have looked at intake of foods in the context of a whole diet. Therefore, including lycopene-rich foods is recommended over taking a supplement. LYCOPENE-RICH FOODS: The best way to include lycopene in your diet is to eat more processed tomato products. Research shows the body better absorbs lycopene when tomatoes are processed. While raw tomatoes have some lycopene, it takes more of them to make the processed foods, meaning there is more lycopene in each serving. Below is a list of foods and their lycopene content:
Lycopene Content in Foods (mg/100g)
Tomato Paste 42.2
Spaghetti Sauce 21.9
Chili Sauce 19.5
Tomato Ketchup 15.9
Tomato Juice 9.5
Pink Grapefruit 4.0
Raw Tomato 3.0

You can visit knolhub to know more about the Dyson DC08 Vacuum cleaner.

Bush’s Trillion $ LIES About SS

WASHINGTON, Oct. 26 /PRNewswire/ — The Susan G. Komen Breast Cancer Foundation, credited as the nation’s leading catalyst in the fight against breast cancer, released today a non-partisan comparison of key health care proposals announced by Vice President Gore and Governor Bush in their quest for the Presidency.  The comparison is based on answers to a health care questionnaire designed by the Komen Foundation, to which both campaigns responded.  The Foundation hopes that the side-by-side analysis of the candidates’ varying proposals will assist voters in comparing and contrasting the approach each would take to important health care issues impacting women and families.

As a leader in the healthcare arena, the Susan G. Komen Breast Cancer Foundation has consistently promoted a broad range of issues impacting women and families.  The Komen Foundation, a bipartisan non-profit organization, works to educate women throughout the United States about the importance of these issues in their daily lives.

The Komen Foundation is an international organization with 114 domestic Affiliates in 45 states and the District of Columbia, as well as three Affiliates in Germany, Greece and Italy.  Since its inception, the Komen Foundation has raised more than $300 million to support breast cancer research, education, and screening and treatment programs.  These programs include cutting-edge basic, clinical and translational breast cancer research, and innovative outreach programs in local communities to assist the medically underserved.  The Susan G. Komen Breast Cancer Foundation is a nonpartisan charitable organization that does not endorse or oppose any candidate for public office

‘Green’ terrorists set back cancer research

What if the knowledge that scientists might have gained about the cancer-like tree disease referred to below could have led to a cure for human cancer?
As an environmentalist myself I know that the possibility that greater scientific knowledge of plants and their diseases may lead to breakthroughs in the treatment and even cures of many human and animal
diseases.

“This group is sick. They damaged a program that is for the good of everyone. We feel personally violated.” — Jud Isebrands, scientist at federal forestry research center near Rhinelander. Calling it “an attack against bio-engineering,” a group of radical environmentalists said it destroyed 500 research trees and spray-painted graffiti on vehicles at a federal forestry laboratory near Rhinelander, officials said Friday.

The Seattle-based North American Earth Liberation Front, an underground environmental activist organization, claimed responsibility for killing rare nursery stock worth $750,000 and vandalizing eight vehicles at a research station run by the U.S. Forestry Sciences Laboratory. Using saws and machetes to cut down the trees, and then trampling on them, the group short-circuited a 30-year project aimed at finding a cure for a cancer-like disease that attacks poplar trees, said Jud Isebrands, a scientist at the facility.

In the Thursday night attack, the group painted large green-and-black slogans on automobiles that warned: “ELF is watching the U.S. Forest Service.” The group also spread acid on windshields, Isebrands said. Damage to vehicles was estimated at $20,000, he said. The ELF, which has claimed responsibility for 13 attacks causing $31 million in damages over the last six years, opposes manipulating genetic matter in plants and animals, said Craig Rosebraugh, the group’s spokesman.

At least four separate anti-bio-engineering groups have carried out more than 30 attacks this year at facilities that included strawberry and sugar beet fields in California, cornfields in Maine and a grass field in Oregon. But researchers at the Rhinelander nursery had not used bio- engineering methods on any of the trees that were destroyed, said Isebrands, a member of a team working to find a cure for septoria canker, a disease that forms tumor-like swellings on poplar trees, causing millions of dollars in damage nationwide.

“This was not bio-technology,” Isebrands said. “All of our work was done using traditional plant-breeding techniques that have been around for years. We simply took a genetically superior tree and matched it with another tree. Then you just hope to get a better plant.” Besides poplars, the attackers destroyed young red oaks and other tree species.

“This group is sick,” Isebrands said. “They damaged a program that is for the good of everyone. We feel personally violated. We run this area like a public park. It’s open to everyone. We don’t want to put razor wire around here.” The attack set back the research project by 10 to 15 years, Isebrands said. About 10 members of the research team had been preparing stock that requires about 10 years for each generation to mature before scientists can move on to the next phase.

ELF has taken credit for six similar attacks this year, including a New Year’s Eve incident involving a suite of offices at the Michigan State University’s Agriculture Hall. “ELF is definitely stepping up its actions,” Rosebraugh said. Rosebraugh said he was not a member of the group, but he received information from members, who remained anonymous.

ELF members work in small cells, he said, and members do not know the identity of members in other cells. The Wisconsin attack probably identity of members in other cells. The Wisconsin attack probably was conducted by members from outside the state, he said. To avoid getting caught, members rarely conduct attacks in their home states, he said.

2000CRE1167C BREAST CANCER RESEARCH STAMP REAUTHORIZATION ACT OF 2000

Mr. LAZIO. Mr. Speaker, I rise to introduce the bill entitled the Breast Cancer Research Stamps Reauthorization Act of 2000.
Breast cancer is the most commonly diagnosed cancer among women in the United States. More than 2 million American women are currently living with the disease, 1 million of whom have yet to be diagnosed. This year alone, 182,800 women will be diagnosed with breast cancer. Over 40,000 of them will lose their battle with this killer.
Breast cancer has taken an awful toll on the people of my home state. New York has the second-highest breast cancer mortality rate in the country. Between 1980 and 1994, the incidence of breast cancer in New York increased nearly 18 percent. Enactment of this bill will go a long way toward helping our effort to increase funding for breast cancer research. Only through the help of continued cancer research have more and more people become cancer survivors in recent years.
Since the issuance of the Breast Cancer Research stamp in the summer of 1998, 164 million Breast Cancer Research stamps have been sold rising over $12 million for breast cancer research. The stamp provides a convenient avenue for participation in the battle against this horrible disease. Unfortunately, without congressional intervention, the stamp will expire on July 28, 2000. Valuable research funds, as well as a mechanism to heighten public awareness of this horrible disease, will be lost.
This bill, The Breast Cancer Research Stamp Reauthorization Act of 2000 would extend the sale of the Breast Cancer Research stamp for an additional two years. The stamp would continue to cost 40 cents and sell as a first class stamp. The additional funds that are raised will go directly to breast cancer research at the National Institutes of Health and the Department of Defense.
I am pleased to report that this reauthorization bill has tremendous support throughout the health community. Supporters of the Breast Cancer Stamp Reauthorization Act of 2000 include the American Cancer Society, the American Medical Association, the Y-Me National Breast Cancer Organization, Leadership America, the National Association of Women’s Health, the American Cancer League, the American College of Surgeons, Friends of Cancer Research, and many others.
A Breast Cancer Research Stamp remains just as necessary today as it was when this authority was signed into law two years ago. According to the American Association for Cancer Research, 8 million people are alive today as a result of cancer research. To say that every dollar we continue to raise will save lives, can only underscore the importance of this legislation.
I urge my colleagues to join me in enacting this important legislation.

 

Vitamin D Receptor Polymorphisms and Cancer Risk

PHILADELPHIA Subtle differences in the receptor for vitamin D reverse the anti-cancer action of the sunshine vitamin, increasing the risk of breast cancer in Caucasian women and prostate cancer in African-American men, according to two new studies. The results, in journals published by the American Association for Cancer Research, underscore how naturally-occurring variants of the same gene, called polymorphisms, can have implications for cancer initiation and progression.

For example, in the breast cancer study, British scientists at St. George¹s Hospital Medical School in London found that Caucasian women, who carried specific versions of the vitamin D receptor gene, or VDR, not only experienced increased risk for this cancer but may also be more prone to developing metastases.

Differences in the gene sequence for the vitamin D receptor are associated with breast cancer risk and may also be linked to disease progression said Kay Colston, Ph.D., the senior author of the study, published in the August 15 issue of the journal Clinical Cancer Research. Colston is a Reader in the Department of Cellular and Molecular Medicine at St. George¹s Hospital Medical School.

Among three known variable regions of the VDR gene considered by the research team, the bb and LL variants increased breast cancer risk by almost twofold. The F variant of the gene had no significant effect on breast cancer risk by itself, however when coupled with the LL genotype the risk of breast cancer was increased by a higher factor than the bb or LL genotypes alone. In addition, there was a higher proportion of women with this Œat risk genotype in a sub-group of patients who developed metastatic disease.

A second study, conducted independently, linked a similar change in the vitamin D receptor (VDR) with amplified risk of prostate cancer for African American men. That study appeared in the August issue of Cancer Epidemiology, Biomarkers & Prevention, a sister publication to Clinical Cancer Research.

Intriguingly, the F variant that increases the chance of developing breast cancer when associated with other VDR variants also contributes to increased risk and aggressiveness of prostate cancer in African-American men, according to the Cancer Epidemiology, Biomarkers & Prevention article. This study reported that men with two copies of the F variant almost doubled the risk for prostate cancer developing in African-Americans, but not Caucasians. Furthermore, the same men had twice the risk for developing high grade advanced prostate cancer, according to the research.

More African-American prostate cancer patients carried the homozygous FF variant of the vitamin D receptor than African American men who did not have prostate cancer, said Alice S. Whittemore, Ph.D., the senior author of the paper. Whittemore, who conducts cancer research in the department of Health Research and Policy, the Stanford University School of Medicine, led a multi-institutional team of cancer scientists from Stanford University, the University of Southern California, the University of Hawaii, the British Columbia Cancer Agency and the Northern California Cancer Center.

Neither the b nor L gene variants that altered risk in Caucasian women in the British study contributed to elevated risk for prostate cancer among men. Funding for the prostate cancer studies came from NIH grant CA67044. The UK breast cancer study was funded by Breast Cancer Campaign and the World Cancer Research Fund.

 

BREAST CANCER RESEARCH — Buy Postage Stamps!!

As you may be aware, the US Postal Service recently released its new “Fund the Cure” stamp to help fund breast cancer research. The stamp was designed by Ethel Kessler of Bethesda, Maryland.  It is important that we take a stand against this disease that kills and maims so many of our mothers, sisters, and friends.

Instead of the normal $.33 for a stamp, this one costs $.40.  The additional $.07 will go to breast cancer research.  A “normal” book costs $6.60.  This one is only $8.00. It takes a few minutes in line at the Post Office and means so much.  If all stamps are sold, it will raise an additional $16,000,000 for this vital research. Many of us know women and their families whose lives are turned upside-down by breast cancer.  It takes so little to do so much in this drive.

While I have no objection to the issuance of semi-postal stamps to fund breast cancer research, I think that is is a self-deception.  The cure, if that is the correct term, is most likely to come from fundamental biological research pursued by biologists that are not quite so goal oriented to meet their sponsors’ desires.

During Nixon’s presidency, a “war” on cancer was started.  More than 20 years later the biggest steps to fight cancer have come from mainline biological research into subjects like genetics, angiogenesis, drug action, etc.  While the money spent was not wasted, it was not used efficiently.  The goal oriented research tries to tackle problems for which the science is not available.  It does sound good, however, to the desperate suffering from the disease.  In a sense, the science for a cure is not here yet.

It should be obvious to this group that arthritis has not been cured although fundamental knowledge has greatly increased.  The result has been better treatments.  Realize however, that study of autoimmune disease and immunity in general, for example, is what will pay dividends for BOTH arthritis and breast cancer therapy.

We also see another useless war in action.  The war on drugs.  It too is a means to divert resources into the pockets of special interests while doing little to solve our nation’s drug problems. I just had to get on my soap box.  It irks me to see people following panaceas that will only prove to be a disappointment.  The main advantage, not to be underated, is that it makes people feel emotionally better.

 

 

Run for breast cancer research

I am not sure if you have or haven’t heard about this.  Next summer there will be a cross-Canada run that will be in the fund-rasing spirit for fighting breast cancer.  Janet Blades proposed thata similar venture be taken in the US as well, at the same time as the Canada run.  I responded, but alas I am inundated with school and cannot be of any use it seems.  So I will pass the word on, and any brave souls wishing to take up this cause may do so.  Please email me or Janet (I don’t think she’ll mind - if she does blame me) about any questions, but Janet’s the one to really turn to for answers.

I imported my proposal that I sent to the Canadian Cancer Society to the E-Mail, however, it’s tabs are out of whack, but you can get the idea. Try contacting a breast cancer research place, or the American Cancer Society or whoever, with a proposal of your own. Basically our accommodations are with the van (motor home thing) and food I will cover as I have to eat anyway!

There is a lot of work to be done, including trying to find sponsorship for the event, believe me, this is difficult.  However, you have a lot going for you.  You are in University; therefore you have a lot of people you can approach for help.  Try to form a committee as no-one can do it all alone. Decide on a route, find State Coordinators, who will in turn find county coords, who will in turn find runners, you hope.

There has been some interest through the rec.running.  If you decide that you can do this, post it.  If you decide that you’d love to help somebody else coordinate it, post that too, you never know, someone may want to do it but is scared of all of the responsibility/time etc. it would take.  Team work is the best thing to go for.  Because you’re in university, you could contact Universities in each state that you plan on going through for help.

See what you want to do before you go ahead it’s a big undertaking, but would look fantastic on a resume!!!! If you post your interest in the rec.running, you not only get potential coordinators, you get folks who want to run for a full day, I even got a guy who wants to be the sole runner for the whole event.  This is nice, but it defeats the purpose of reaching out to people, uniting the country in a common goal, spreading the word on breast cancer.

 

Reiki Breast Cancer Research Initiative

Useful pointers to ongoing research as we investigate questions of science, spirit and healing.
Nursing researcher receives funding for unconventional breast cancer therapy
Dr. Ahlam Mansour, of the College of Nursing, has received a $20,000 grant from the Canadian Breast Cancer Research Initiative (CBCRI) to conduct a feasibility study of the effects of Reiki. The grant is one of only six awarded in a national competition in which 47 submissions were received by the CBCRI, which is a granting agency housed in the National Cancer Institute of Canada, Toronto.

Dr. Mansour, herself a second-degree Reiki says there’s an abundance of anecdotal records and some emerging scientific evidence that Reiki is effective in decreasing physical problems and anxiety associated with illness. She adds, “no rigorous studies have been undertaken into its efficacy. Our study will be to investigate the effects of Reiki on the level of anxiety, physical problems, spiritual well-being, and complete blood counts in breast cancer patients undergoing their initial (AC) chemotherapy.”

She says she and her nine-person team* will soon begin a partially-blind, placebo-controlled clinical trial to test for the effectiveness of the therapy.

“We hope that the feasibility study will provide enough data to determine whether or not to proceed to a full-scale study on the efficacy of Reiki in reducing the side-effects of chemotherapy and the emotional problems breast cancer patients generally experience.”

* The team members include: Dr. Mansour; Dr. Gail Laing, a professor in Nursing; Marion Bueche, a Reiki master, who practices in Regina; Dr. Barbara Walley, an oncologist at the Saskatoon Cancer Clinic; Dr. Anne Leis, a psychologist in Community Health and Epidemiology (CHE); Dr. Alanna Danilkewich, a family physician at the RUH; Judy Nurse, a research coordinator in CHE; and Pat Homenick, Peg Schmidt, and Olga Stefaniuk, breast cancer survivors.

Chronic Illness Study:
Martha Lucas, Ph.D., is the research advisor for an international Reiki Research Project. The project is still waiting funding (a mere $9500) but already has Reiki practitioners volunteering daily, with several “area coordinators” all over the country.

This research project will be working with patients who are suffering with AIDS, diabetes, migraines, and MS. If you know anyone who needs help with any of these disorders, they may participate with no cost to them.

We will be working on clients with AIDS or diabetes or migraine headaches. Some will receive Reiki, some will be taught to give Reiki to themselves, and some will involve practitioner and self-application. Group 4 will be on the “waiting list.”