COMPANY
Well-equipped U.S. research headquarters of international drug discovery company. Attractive campus. Excellent resources. High caliber of science. Company is committed to cutting edge research. Provides cutting-edge tools and support. Highly collaborative environment.
DESCRIPTION
Cell biology associate scientist for a cancer research group heavily focused on breast cancer. Apply 3 to 5 years of relevant experience ideally acquired within an industrial biotech environment.
RESPONSIBILITIES
Within a cell biology department, support cancer research genomics program focused on breast cancer. Apply knowledge in cell biology, cell based assays, cell-cell and cell-matrix signaling mechanisms, and antibody experience. Develop, optimize and perform cell-based assays to evaluate novel-gene therapeutic candidates. Validate novel protein drug targets utilizing strategies such as neutralizing antibodies and anti-sense oligonucleotide-based gene knock-outs. Another validation method used will be transfections of wild-type and dominant negative protein.
LOCATION
San Francisco Bay Area.
QUALIFICATIONS
BS or MS in cell biology with 3 to 5 years of pertinent experience, ideally within an industrial biotech setting. Broad knowledge of cell biology. Cell based assay experience (ex: proliferation, apoptosis, migrations and/or invasion assays). Experience working with cancer cell lines. The ability to manipulate a cell is important. Two crucial areas of technical knowledge are: 1.) Mammalian cell transfection and 2.) Delivering antisense oligonucleotides. Ideally we are seeking experience in the culture and transfection of primary and established human cell lines. Strong interpersonal and problem solving skills also important..
DESIRED (Not Mandatory)
Possible growth factor experience. Extracellular matrix interaction. Familiarity with: DNA expression vectors. Antisense olignucleotides. Immuno-cytochemistry and antibody characterization. Molecular biology techniques: such as cDNA cloning, DNA and RNA isolation. Northern and Western blot analysis.
COMPENSATION
Competitive salary and benefits.
LOS ANGELES- the Postal Service unveiled the design of the Breast Cancer Research “Semipostal” Stamp, here, at the Revlon Run and Walk for Women on May 9th. A nationwide issuance of this self-adhesive stamp begins in early August.
BACKGROUND: Harvard researchers reported in a 2002 article in the Journal of the National Cancer Institute that eating tomato products on a regular basis is associated with a reduced risk of prostate cancer. The research included more than 47,000 participants. Researchers then continued to follow the men for several more years to learn more about the specific foods that seem to protect men from prostate cancer. That research was published this year — also in the Journal of the National Cancer Institute. The study reports men who ate tomato sauce at least twice a week were about 20-percent less likely to develop prostate cancer when compared to men who rarely ate it.
Associated Press
WASHINGTON, Oct. 26 /PRNewswire/ — The Susan G. Komen Breast Cancer Foundation, credited as the nation’s leading catalyst in the fight against breast cancer, released today a non-partisan comparison of key health care proposals announced by Vice President Gore and Governor Bush in their quest for the Presidency. The comparison is based on answers to a health care questionnaire designed by the Komen Foundation, to which both campaigns responded. The Foundation hopes that the side-by-side analysis of the candidates’ varying proposals will assist voters in comparing and contrasting the approach each would take to important health care issues impacting women and families.
What if the knowledge that scientists might have gained about the cancer-like tree disease referred to below could have led to a cure for human cancer?
PHILADELPHIA Subtle differences in the receptor for vitamin D reverse the anti-cancer action of the sunshine vitamin, increasing the risk of breast cancer in Caucasian women and prostate cancer in African-American men, according to two new studies. The results, in journals published by the American Association for Cancer Research, underscore how naturally-occurring variants of the same gene, called polymorphisms, can have implications for cancer initiation and progression.
As you may be aware, the US Postal Service recently released its new “Fund the Cure” stamp to help fund breast cancer research. The stamp was designed by Ethel Kessler of Bethesda, Maryland. It is important that we take a stand against this disease that kills and maims so many of our mothers, sisters, and friends.


